Founder, Clinical Director

Lori Vasquez, PMHNP-BC, is a board-certified Psychiatric-Mental Health Nurse Practitioner serving patients in Newport Beach, Irvine, and across California via telehealth. With over a decade of nursing experience, including emergency psychiatry, crisis stabilization, and outpatient care, she brings both clinical depth and calm presence to every visit.

She earned her Bachelor of Science in Nursing from Ohio University and her Master’s degree with honors from Walden University.

Lori specializes in medication management for ADHD, anxiety disorders, depression, and perinatal mood conditions, including postpartum depression and anxiety. She works with teens and adults who are seeking thoughtful, evidence-based psychiatric care that feels collaborative rather than rushed.

Her philosophy is simple: mental health care should feel human. She takes time to understand the full picture — symptoms, stressors, lifestyle, and goals — developing personalized treatment plans that help patients stabilize, regain confidence, and return to the parts of life that matter most.

Operations, Creative Director

As RN and co-founder of Mind Over Matter Psychiatry, Matt makes sure the practice runs smoothly behind the scenes so patients and families get fast access to care — without all the red tape.

With nearly a ten year background in critical care and behavioral health, Matt has a passion for making sure our patients get the best care, and feel taken care of.

He is also a children’s book author, and part time puppeteer on the Unicorn Jazz series — which is a fun reminder that healing, play, and connection are powerful at any age.

Behind all of it is one simple goal:
to make mental healthcare more human, accessible, and efficient for the people who need it.

Supervising Physician

Dr. Jennie Byrne is a board-certified psychiatrist and neuroscientist with deep experience in clinical care, leadership, and healthcare innovation. She has served as a founder, national C-level leader, and advisor to multiple mental health companies that are reshaping how care is delivered across the U.S.

With both an MD and PhD in neuroscience, Dr. Byrne brings a unique, evidence-based perspective to psychiatry — connecting biology, behavior, and real-world patient outcomes. She has helped build and scale mental health programs from inception to exit, and continues to advise organizations driving the future of care through technology, data, and better access.

At Mind Over Matter, Dr. Byrne provides clinical supervision, mentorship, and oversight — ensuring our care stays aligned with the highest standards of safety, integrity, and clinical excellence.